4lli

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{{STRUCTURE_4lli| PDB=4lli | SCENE= }}
 
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===Crystal Structure of human Myosin 5a globular domain===
 
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==Disease==
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==Crystal Structure of human Myosin 5a globular domain==
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[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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<StructureSection load='4lli' size='340' side='right'caption='[[4lli]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4lli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LLI FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lli OCA], [https://pdbe.org/4lli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lli RCSB], [https://www.ebi.ac.uk/pdbsum/4lli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lli ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[4lli]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LLI OCA].
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== Disease ==
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[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Griscelli disease type 3;Neuroectodermal melanolysosomal disease;Griscelli disease type 1. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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==Reference==
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== Function ==
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<references group="xtra"/><references/>
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[https://www.uniprot.org/uniprot/MYO5A_HUMAN MYO5A_HUMAN] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:10448864</ref>
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[[Category: Niessing, D.]]
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== References ==
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[[Category: Velvarska, H.]]
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<references/>
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[[Category: Dilute domain]]
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__TOC__
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[[Category: Globular tail]]
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</StructureSection>
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[[Category: Motor protein]]
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[[Category: Homo sapiens]]
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[[Category: Type v myosin]]
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[[Category: Large Structures]]
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[[Category: Niessing D]]
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[[Category: Velvarska H]]

Current revision

Crystal Structure of human Myosin 5a globular domain

PDB ID 4lli

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