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JMS/sandboxBarkai

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Current revision (14:47, 25 December 2013) (edit) (undo)
 
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<StructureSection load='1mbn' size='350' side='right' caption='myoglobin - how the chain cradles the heme (PDB entry [[1mbn]])' scene='55/557585/Align_test/5'>
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<StructureSection load='1mbn' size='350' side='right' caption='myoglobin (PDB entry [[1mbn]])' scene='55/557585/Align_test/5'>
It comes down to <scene name='55/557585/Align_test/18'>eight divergent amino acids (elephant's amino acids in yellow halos, whale next to it, without halos)</scene>. Without these amino acids, myoglobin in both whale and elephants has a charge of ''+1''. With them, whale myoglobin has net charge of ''+4'', which is significantly higher than elephants' ''+2''. Importantly, all eight of these divergent amino acids are <scene name='52/523344/Elephantwhale/34'>surface residues</scene>.
It comes down to <scene name='55/557585/Align_test/18'>eight divergent amino acids (elephant's amino acids in yellow halos, whale next to it, without halos)</scene>. Without these amino acids, myoglobin in both whale and elephants has a charge of ''+1''. With them, whale myoglobin has net charge of ''+4'', which is significantly higher than elephants' ''+2''. Importantly, all eight of these divergent amino acids are <scene name='52/523344/Elephantwhale/34'>surface residues</scene>.

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myoglobin (PDB entry 1mbn)

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Joseph M. Steinberger

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