4m1m
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4m1m| PDB=4m1m | SCENE= }} | ||
| - | ===Corrected Structure of Mouse P-glycoprotein=== | ||
| - | {{ABSTRACT_PUBMED_24155053}} | ||
| - | == | + | ==Corrected Structure of Mouse P-glycoprotein== |
| - | [[ | + | <StructureSection load='4m1m' size='340' side='right'caption='[[4m1m]], [[Resolution|resolution]] 3.80Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4m1m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M1M FirstGlance]. <br> |
| - | [[4m1m]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m1m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m1m OCA], [https://pdbe.org/4m1m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m1m RCSB], [https://www.ebi.ac.uk/pdbsum/4m1m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m1m ProSAT]</span></td></tr> |
| - | < | + | </table> |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> |
| - | [ | + | == References == |
| - | [ | + | <references/> |
| - | + | __TOC__ | |
| - | [ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Aller SG]] |
| - | [[Category: | + | [[Category: Jaimes KF]] |
| - | [[Category: | + | [[Category: Li J]] |
Current revision
Corrected Structure of Mouse P-glycoprotein
| |||||||||||
