4hsb

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{{STRUCTURE_4hsb| PDB=4hsb | SCENE= }}
 
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===S. pombe 3-methyladenine DNA glycosylase-like protein Mag2 bound to damaged DNA===
 
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{{ABSTRACT_PUBMED_23273506}}
 
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==Function==
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==S. pombe 3-methyladenine DNA glycosylase-like protein Mag2 bound to damaged DNA==
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[[http://www.uniprot.org/uniprot/MAG2_SCHPO MAG2_SCHPO]] Invlved in base excision repair of methyl methanesulfonate-damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.<ref>PMID:18270439</ref>
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<StructureSection load='4hsb' size='340' side='right'caption='[[4hsb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4hsb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HSB FirstGlance]. <br>
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[[4hsb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSB OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hsb OCA], [https://pdbe.org/4hsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hsb RCSB], [https://www.ebi.ac.uk/pdbsum/4hsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hsb ProSAT]</span></td></tr>
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<ref group="xtra">PMID:023273506</ref><references group="xtra"/><references/>
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</table>
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[[Category: DNA-3-methyladenine glycosylase II]]
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== Function ==
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[[Category: Fission yeast]]
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[https://www.uniprot.org/uniprot/MAG2_SCHPO MAG2_SCHPO] Invlved in base excision repair of methyl methanesulfonate-damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.<ref>PMID:18270439</ref>
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[[Category: Adhikary, S.]]
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== References ==
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[[Category: Eichman, B F.]]
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<references/>
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[[Category: Helix-hairpin-helix]]
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__TOC__
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[[Category: Hydrolase-dna complex]]
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</StructureSection>
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[[Category: Non-specific dna-binding motif]]
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[[Category: Large Structures]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Adhikary S]]
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[[Category: Eichman BF]]

Current revision

S. pombe 3-methyladenine DNA glycosylase-like protein Mag2 bound to damaged DNA

PDB ID 4hsb

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