4lng

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{{STRUCTURE_4lng| PDB=4lng | SCENE= }}
 
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===Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib===
 
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{{ABSTRACT_PUBMED_24347326}}
 
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==About this Structure==
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==Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib==
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[[4lng]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNG OCA].
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<StructureSection load='4lng' size='340' side='right'caption='[[4lng]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lng]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LNG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.905&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FPP:FARNESYL+DIPHOSPHATE'>FPP</scene>, <scene name='pdbligand=JAN:6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE'>JAN</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lng OCA], [https://pdbe.org/4lng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lng RCSB], [https://www.ebi.ac.uk/pdbsum/4lng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lng ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4WP27_ASPFU Q4WP27_ASPFU]
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==Reference==
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==See Also==
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<ref group="xtra">PMID:024347326</ref><references group="xtra"/><references/>
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*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
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[[Category: Protein farnesyltransferase]]
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__TOC__
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[[Category: Beese, L S.]]
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</StructureSection>
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[[Category: Hast, M A.]]
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[[Category: Aspergillus fumigatus Af293]]
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[[Category: Mabanglo, M F.]]
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[[Category: Large Structures]]
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[[Category: Farnesylation]]
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[[Category: Beese LS]]
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[[Category: Farnesyltransferase]]
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[[Category: Hast MA]]
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[[Category: Isoprenoid and caax-containing protein and peptide substrate]]
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[[Category: Mabanglo MF]]
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[[Category: Prenylation]]
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[[Category: Transferase]]
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Current revision

Aspergillus fumigatus protein farnesyltransferase complex with farnesyldiphosphate and tipifarnib

PDB ID 4lng

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