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4nsw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the BAR-PH domain of ACAP1== | |
| - | + | <StructureSection load='4nsw' size='340' side='right'caption='[[4nsw]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4nsw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NSW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nsw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nsw OCA], [https://pdbe.org/4nsw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nsw RCSB], [https://www.ebi.ac.uk/pdbsum/4nsw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nsw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ma J]] | ||
| + | [[Category: Pang X]] | ||
| + | [[Category: Sun F]] | ||
| + | [[Category: Zhang K]] | ||
| + | [[Category: Zhou Q]] | ||
Current revision
Crystal structure of the BAR-PH domain of ACAP1
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Categories: Homo sapiens | Large Structures | Ma J | Pang X | Sun F | Zhang K | Zhou Q
