4m8n

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{{STRUCTURE_4m8n| PDB=4m8n | SCENE= }}
 
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===Crystal Structure of PlexinC1/Rap1B Complex===
 
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{{ABSTRACT_PUBMED_24137545}}
 
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==Function==
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==Crystal Structure of PlexinC1/Rap1B Complex==
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[[http://www.uniprot.org/uniprot/RAP1B_HUMAN RAP1B_HUMAN]] GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction.<ref>PMID:20332120</ref> <ref>PMID:18660803</ref>
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<StructureSection load='4m8n' size='340' side='right'caption='[[4m8n]], [[Resolution|resolution]] 3.29&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4m8n]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M8N FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.294&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AF3:ALUMINUM+FLUORIDE'>AF3</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m8n OCA], [https://pdbe.org/4m8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m8n RCSB], [https://www.ebi.ac.uk/pdbsum/4m8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m8n ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5RGW1_DANRE Q5RGW1_DANRE]
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==About this Structure==
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==See Also==
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[[4m8n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8N OCA].
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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*[[Plexin 3D structures|Plexin 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:024137545</ref><references group="xtra"/><references/>
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</StructureSection>
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[[Category: Brachidanio rerio]]
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[[Category: Danio rerio]]
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Brautigam, C A.]]
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[[Category: Large Structures]]
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[[Category: He, H.]]
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[[Category: Brautigam CA]]
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[[Category: Pascoe, H G.]]
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[[Category: He H]]
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[[Category: Wang, Y.]]
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[[Category: Pascoe HG]]
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[[Category: Zhang, X.]]
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[[Category: Wang Y]]
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[[Category: Gtp binding]]
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[[Category: Zhang X]]
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[[Category: Gtpase]]
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[[Category: Gtpase activating protein]]
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[[Category: Magnesium binding]]
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[[Category: Membrane]]
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[[Category: Rap]]
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[[Category: Signaling protein]]
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Current revision

Crystal Structure of PlexinC1/Rap1B Complex

PDB ID 4m8n

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