4n5b
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4n5b| PDB=4n5b | SCENE= }} | ||
| - | ===Crystal structure of the Nipah virus phosphoprotein tetramerization domain=== | ||
| - | {{ABSTRACT_PUBMED_24155387}} | ||
| - | == | + | ==Crystal structure of the Nipah virus phosphoprotein tetramerization domain== |
| - | [[4n5b]] is a 8 chain structure with sequence from [ | + | <StructureSection load='4n5b' size='340' side='right'caption='[[4n5b]], [[Resolution|resolution]] 2.20Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4n5b]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Nipah_henipavirus Nipah henipavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N5B FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n5b OCA], [https://pdbe.org/4n5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n5b RCSB], [https://www.ebi.ac.uk/pdbsum/4n5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n5b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D2DEB8_NIPAV D2DEB8_NIPAV] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The Nipah virus phosphoprotein, P, is multimeric and tethers the viral polymerase to the nucleocapsid. We present the crystal structure of the multimerization domain of Nipah P: a long, parallel, tetrameric, coiled coil with a small, alpha-helical cap structure. Across the paramyxoviruses, these domains share little sequence identity; yet retain similar length and structural organization, suggesting a common requirement for scaffolding or spatial organization of the functions of P in the virus life cycle. | ||
| - | + | Crystal structure of the Nipah virus phosphoprotein tetramerization domain.,Bruhn-Johannsen JF, Barnett K, Bibby J, Thomas J, Keegan R, Rigden D, Bornholdt ZA, Saphire EO J Virol. 2013 Oct 23. PMID:24155387<ref>PMID:24155387</ref> | |
| - | <ref | + | |
| - | [[Category: | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | [[Category: Barnett | + | </div> |
| - | [[Category: Bibby | + | <div class="pdbe-citations 4n5b" style="background-color:#fffaf0;"></div> |
| - | [[Category: Bornholdt | + | == References == |
| - | [[Category: Bruhn | + | <references/> |
| - | [[Category: Keegan | + | __TOC__ |
| - | [[Category: Rigden | + | </StructureSection> |
| - | [[Category: Saphire | + | [[Category: Large Structures]] |
| - | [[Category: Thomas | + | [[Category: Nipah henipavirus]] |
| - | + | [[Category: Barnett K]] | |
| - | + | [[Category: Bibby J]] | |
| - | + | [[Category: Bornholdt ZA]] | |
| - | + | [[Category: Bruhn JF]] | |
| + | [[Category: Keegan R]] | ||
| + | [[Category: Rigden D]] | ||
| + | [[Category: Saphire EO]] | ||
| + | [[Category: Thomas J]] | ||
Current revision
Crystal structure of the Nipah virus phosphoprotein tetramerization domain
| |||||||||||
Categories: Large Structures | Nipah henipavirus | Barnett K | Bibby J | Bornholdt ZA | Bruhn JF | Keegan R | Rigden D | Saphire EO | Thomas J
