3pz2

{{STRUCTURE_3pz2| PDB=3pz2 | SCENE= }}

===Crystal structure of RabGGTase(DELTA LRR; DELTA IG) in Complex with BMS3 and lipid substrate GGPP===

==Function==

[[http://www.uniprot.org/uniprot/PGTA_RAT PGTA_RAT]] Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively. [[http://www.uniprot.org/uniprot/PGTB2_RAT PGTB2_RAT]] Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

==About this Structure==

[[3pz2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZ2 OCA].

 

<ref group="xtra">PMID:021520375</ref><references group="xtra"/><references/>

[[Category: Lk3 transgenic mice]]

[[Category: Protein geranylgeranyltransferase type II]]

[[Category: Alexandrov, K.]]

[[Category: Blankenfeldt, W.]]

[[Category: Bon, R S.]]

[[Category: Goody, R S.]]

[[Category: Guo, Z.]]

[[Category: Stigter, E A.]]

[[Category: Waldmann, H.]]

[[Category: Transferase-transferase inhibitor complex]]