2yxx
From Proteopedia
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| - | [[Image:2yxx.gif|left|200px]]<br /><applet load="2yxx" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2yxx, resolution 1.70Å" /> | ||
| - | '''Crystal structure analysis of Diaminopimelate decarboxylate (lysA)'''<br /> | ||
| - | == | + | ==Crystal structure analysis of Diaminopimelate decarboxylate (lysA)== |
| - | + | <StructureSection load='2yxx' size='340' side='right'caption='[[2yxx]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2yxx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YXX FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
| + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diaminopimelate_decarboxylase Diaminopimelate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.20 4.1.1.20] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxx OCA], [http://pdbe.org/2yxx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxx RCSB], [http://www.ebi.ac.uk/pdbsum/2yxx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxx ProSAT], [http://www.topsan.org/Proteins/RSGI/2yxx TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/DCDA_THEMA DCDA_THEMA]] Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine (By similarity).[HAMAP-Rule:MF_02120] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxx_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yxx ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Diaminopimelate decarboxylase]] | [[Category: Diaminopimelate decarboxylase]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Thema]] |
| - | [[Category: Bessho, Y | + | [[Category: Bessho, Y]] |
| - | [[Category: Nakamura, Y | + | [[Category: Nakamura, Y]] |
| - | [[Category: Padmanabhan, B | + | [[Category: Padmanabhan, B]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Yokoyama, S | + | [[Category: Yokoyama, S]] |
| - | [[Category: | + | [[Category: Lyase]] |
| - | [[Category: | + | [[Category: National project on protein structural and functional analyse]] |
| - | + | [[Category: Nppsfa]] | |
| - | [[Category: | + | [[Category: Rsgi]] |
| - | [[Category: | + | [[Category: Tim beta/alpha barrel fold]] |
| - | + | [[Category: Tm1517]] | |
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| - | [[Category: | + | |
| - | [[Category: | + | |
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Current revision
Crystal structure analysis of Diaminopimelate decarboxylate (lysA)
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