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4k4o

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{{STRUCTURE_4k4o| PDB=4k4o | SCENE= }}
 
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===The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor===
 
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==Function==
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==The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor==
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[[http://www.uniprot.org/uniprot/Q839Z1_ENTFA Q839Z1_ENTFA]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity).[HAMAP-Rule:MF_01898]
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<StructureSection load='4k4o' size='340' side='right'caption='[[4k4o]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4k4o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_V583 Enterococcus faecalis V583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K4O FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOO:6-FLUORO-4-[(3AR,6AR)-HEXAHYDROPYRROLO[3,4-B]PYRROL-5(1H)-YL]-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE'>DOO</scene>, <scene name='pdbligand=TBU:TERTIARY-BUTYL+ALCOHOL'>TBU</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k4o OCA], [https://pdbe.org/4k4o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k4o RCSB], [https://www.ebi.ac.uk/pdbsum/4k4o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k4o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GYRB_ENTFA GYRB_ENTFA]
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==About this Structure==
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==See Also==
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[[4k4o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K4O OCA].
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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[[Category: Akers-Rodriguez, S.]]
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__TOC__
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[[Category: Bensen, D C.]]
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</StructureSection>
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[[Category: Lam, T.]]
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[[Category: Enterococcus faecalis V583]]
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[[Category: Tari, L W.]]
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[[Category: Large Structures]]
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[[Category: Atp-binding]]
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[[Category: Akers-Rodriguez S]]
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[[Category: Atp-binding domain]]
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[[Category: Bensen DC]]
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[[Category: Cytosol]]
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[[Category: Lam T]]
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[[Category: Isomerase-isomerase inhibitor complex]]
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[[Category: Tari LW]]
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[[Category: Nucleotide-binding]]
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[[Category: Topoisomerase]]
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Current revision

The DNA Gyrase B ATP binding domain of Enterococcus faecalis in complex with a small molecule inhibitor

PDB ID 4k4o

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