3ano

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{{STRUCTURE_3ano| PDB=3ano | SCENE= }}
 
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===Crystal Structure of a Novel Diadenosine 5',5'''-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv===
 
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{{ABSTRACT_PUBMED_21565198}}
 
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==Function==
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==Crystal Structure of a Novel Diadenosine 5',5'''-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv==
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[[http://www.uniprot.org/uniprot/AP4A_MYCTU AP4A_MYCTU]] Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues.<ref>PMID:19778616</ref> <ref>PMID:21565198</ref>
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<StructureSection load='3ano' size='340' side='right'caption='[[3ano]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3ano]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ANO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ANO FirstGlance]. <br>
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[[3ano]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_sp._h37rv Mycobacterium sp. h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ANO OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.894&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ano FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ano OCA], [https://pdbe.org/3ano PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ano RCSB], [https://www.ebi.ac.uk/pdbsum/3ano PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ano ProSAT]</span></td></tr>
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<ref group="xtra">PMID:021565198</ref><references group="xtra"/><references/>
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</table>
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[[Category: ATP adenylyltransferase]]
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== Function ==
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[[Category: Mycobacterium sp. h37rv]]
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[https://www.uniprot.org/uniprot/AP4A_MYCTU AP4A_MYCTU] Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues.<ref>PMID:19778616</ref> <ref>PMID:21565198</ref>
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[[Category: Arakawa, Y.]]
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== References ==
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[[Category: Mori, S.]]
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<references/>
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[[Category: Shibayama, K.]]
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__TOC__
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[[Category: Wachino, J.]]
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</StructureSection>
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[[Category: Diadenosine polyphosphate]]
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[[Category: Large Structures]]
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[[Category: Hit motif]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Mycobacterium]]
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[[Category: Arakawa Y]]
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[[Category: Phosphorylase]]
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[[Category: Mori S]]
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[[Category: Transferase]]
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[[Category: Shibayama K]]
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[[Category: Wachino J]]

Current revision

Crystal Structure of a Novel Diadenosine 5',5-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv

PDB ID 3ano

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