4k34
From Proteopedia
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| - | {{STRUCTURE_4k34| PDB=4k34 | SCENE= }} | ||
| - | ===Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation=== | ||
| - | {{ABSTRACT_PUBMED_24099674}} | ||
| - | == | + | ==Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation== |
| - | [[ | + | <StructureSection load='4k34' size='340' side='right'caption='[[4k34]], [[Resolution|resolution]] 2.69Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4k34]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K34 FirstGlance]. <br> |
| - | [[4k34]] is a 2 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.69Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k34 OCA], [https://pdbe.org/4k34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k34 RCSB], [https://www.ebi.ac.uk/pdbsum/4k34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k34 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/CUSC_ECOLI CUSC_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. In pathogenic strains it allows the bacteria to invade brain microvascular endothelial cells (BMEC) thus allowing it to cross the blood-brain barrier and cause neonatal meningitis.<ref>PMID:11399769</ref> <ref>PMID:12813074</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Su C-C]] | ||
Current revision
Crystal structures of CusC review conformational changes accompanying folding and transmembrane channel formation
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