4nmi
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the Apo ectoine hydroxylase ECTD from Salibacillus salexigens== | |
| + | <StructureSection load='4nmi' size='340' side='right'caption='[[4nmi]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4nmi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Virgibacillus_salexigens Virgibacillus salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NMI FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nmi OCA], [https://pdbe.org/4nmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nmi RCSB], [https://www.ebi.ac.uk/pdbsum/4nmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nmi ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ECTD_VIRSA ECTD_VIRSA] Involved in the biosynthesis of ectoine ((S)-2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid) which is a highly soluble organic osmolyte, called compatible solute, use to avoid excessive water efflux, plasmolysis, molecular crowding of the cytoplasm, and cessation of growth in high salinity environments. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.<ref>PMID:17636255</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Hydroxylases 3D structures|Hydroxylases 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Virgibacillus salexigens]] | ||
| + | [[Category: Bremer E]] | ||
| + | [[Category: Hoeppner A]] | ||
| + | [[Category: Smits SH]] | ||
| + | [[Category: Widderich N]] | ||
Current revision
Crystal Structure of the Apo ectoine hydroxylase ECTD from Salibacillus salexigens
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