361d

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[[Image:361d.gif|left|200px]]<br /><applet load="361d" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="361d, resolution 3.000&Aring;" />
 
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'''CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP'''<br />
 
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==Overview==
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==CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP==
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The synthetic RNA fragment 5'-CUGGGCGG(GCGA)CCGCCUGG (nucleotides in parentheses indicate the loop region) corresponds to the natural sequence of domain E from nucleotides 79-97 of the Thermus flavus 5S rRNA including a hairpin loop. The RNA structure determined at 3.0 A and refined to an R-value of 24.1% also represents the first X-ray structure GNRA tetraloop. The loop is in distinctly different conformation from other GNRA tetraloops analyzed by NMR. The conformation of the two molecules in the asymmetric unit is influenced and stabilized by specific intermolecular contacts. The structural features presented here give evidence for the ability of RNA molecules to adapt to specific environments.
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<StructureSection load='361d' size='340' side='right'caption='[[361d]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[361d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=361D FirstGlance]. <br>
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361D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=361d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=361d OCA], [https://pdbe.org/361d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=361d RCSB], [https://www.ebi.ac.uk/pdbsum/361d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=361d ProSAT]</span></td></tr>
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==Reference==
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</table>
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Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9650592 9650592]
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__TOC__
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[[Category: Protein complex]]
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</StructureSection>
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[[Category: Betzel, C.]]
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[[Category: Large Structures]]
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[[Category: Erdmann, V A.]]
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[[Category: Betzel C]]
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[[Category: Lorenz, S.]]
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[[Category: Erdmann VA]]
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[[Category: Nolte, A.]]
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[[Category: Lorenz S]]
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[[Category: Perbandt, M.]]
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[[Category: Nolte A]]
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[[Category: hairpin]]
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[[Category: Perbandt M]]
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[[Category: mismatched]]
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[[Category: rna]]
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[[Category: single strand]]
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[[Category: tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:02:18 2008''
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Current revision

CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP

PDB ID 361d

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