4oj2
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4oj2 is ON HOLD Authors: Vahedi-Faridi, A., Lodowski, D., Engel, A., Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) Descri...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The structure of aquaporin== |
| + | <StructureSection load='4oj2' size='340' side='right'caption='[[4oj2]], [[Resolution|resolution]] 3.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4oj2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OJ2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oj2 OCA], [https://pdbe.org/4oj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oj2 RCSB], [https://www.ebi.ac.uk/pdbsum/4oj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oj2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | ||
| - | + | ==See Also== | |
| - | + | *[[Aquaporin 3D structures|Aquaporin 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Engel A]] | ||
| + | [[Category: Lodowski D]] | ||
| + | [[Category: Vahedi-Faridi A]] | ||
Current revision
The structure of aquaporin
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