3b4w
From Proteopedia
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| - | [[Image:3b4w.gif|left|200px]]<br /><applet load="3b4w" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="3b4w, resolution 1.80Å" /> | ||
| - | '''Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+'''<br /> | ||
| - | == | + | ==Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+== |
| - | + | <StructureSection load='3b4w' size='340' side='right'caption='[[3b4w]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3b4w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B4W FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b4w OCA], [https://pdbe.org/3b4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b4w RCSB], [https://www.ebi.ac.uk/pdbsum/3b4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b4w ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/P96405_MYCTO P96405_MYCTO] | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b4/3b4w_consurf.spt"</scriptWhenChecked> |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | + | </jmolCheckbox> | |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b4w ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
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| - | [ | + | |
| - | [[ | + | |
| - | [ | + | |
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| - | + | ==See Also== | |
| + | *[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Hung L-W]] | ||
| + | [[Category: Kim C-Y]] | ||
| + | [[Category: Lyon AE]] | ||
| + | [[Category: Moon JH]] | ||
| + | [[Category: Terwilliger T]] | ||
| + | [[Category: Yu M]] | ||
Current revision
Crystal structure of Mycobacterium tuberculosis aldehyde dehydrogenase complexed with NAD+
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