4okg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4okg is ON HOLD Authors: Olivier, N.B., Lahiri, S.D., Prince, D.B. Description: LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[...) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid== | |
| + | <StructureSection load='4okg' size='340' side='right'caption='[[4okg]], [[Resolution|resolution]] 2.06Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4okg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OKG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2SZ:6-(1H-BENZIMIDAZOL-1-YL)-N-HYDROXY-5-[4-({6-[(4-METHYLPIPERAZIN-1-YL)METHYL]PYRIDIN-3-YL}ETHYNYL)PHENYL]PYRIDINE-3-CARBOXAMIDE'>2SZ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4okg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okg OCA], [https://pdbe.org/4okg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4okg RCSB], [https://www.ebi.ac.uk/pdbsum/4okg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4okg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ||
| - | + | ==See Also== | |
| - | + | *[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa PAO1]] | ||
| + | [[Category: Lahiri SD]] | ||
| + | [[Category: Olivier NB]] | ||
| + | [[Category: Prince DB]] | ||
Current revision
LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid
| |||||||||||
