4nuf
From Proteopedia
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| - | {{STRUCTURE_4nuf| PDB=4nuf | SCENE= }} | ||
| - | ===Crystal Structure of SHP/EID1=== | ||
| - | {{ABSTRACT_PUBMED_24379397}} | ||
| - | == | + | ==Crystal Structure of SHP/EID1== |
| - | [[4nuf]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUF OCA]. | + | <StructureSection load='4nuf' size='340' side='right'caption='[[4nuf]], [[Resolution|resolution]] 2.80Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4nuf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O104:H4_str._2009EL-2071 Escherichia coli O104:H4 str. 2009EL-2071] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NUF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nuf OCA], [https://pdbe.org/4nuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nuf RCSB], [https://www.ebi.ac.uk/pdbsum/4nuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nuf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/NR0B2_MOUSE NR0B2_MOUSE] Acts as a transcriptional regulator. Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts. Inhibits transcriptional activity of NEUROD1 on E-box-containing promoter by interfering with the coactivation function of the p300/CBP-mediated trancription complex for NEUROD1.<ref>PMID:8650544</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Maltose-binding protein 3D structures|Maltose-binding protein 3D structures]] | |
| - | [[Category: | + | == References == |
| - | + | <references/> | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli O104:H4 str. 2009EL-2071]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: He Y]] |
| - | [[Category: | + | [[Category: Kliewer SA]] |
| - | [[Category: | + | [[Category: Mangelsdorf DJ]] |
| - | [[Category: | + | [[Category: Melcher K]] |
| - | [[Category: | + | [[Category: Suino-Powell KM]] |
| - | [[Category: | + | [[Category: Xu HE]] |
| - | + | [[Category: Zechner C]] | |
| + | [[Category: Zhi X]] | ||
| + | [[Category: Zhou XE]] | ||
Current revision
Crystal Structure of SHP/EID1
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