2mj7

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{{STRUCTURE_2mj7| PDB=2mj7 | SCENE= }}
 
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===Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C===
 
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==Disease==
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==Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C==
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[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
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<StructureSection load='2mj7' size='340' side='right'caption='[[2mj7]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2mj7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJ7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mj7 OCA], [https://pdbe.org/2mj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mj7 RCSB], [https://www.ebi.ac.uk/pdbsum/2mj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mj7 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
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*[[Adaptin 3D structures|Adaptin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2mj7]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ7 OCA].
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[[Category: Homo sapiens]]
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[[Category: Eletsky, A.]]
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[[Category: Large Structures]]
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[[Category: Everett, J K.]]
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[[Category: Eletsky A]]
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[[Category: Janjua, H.]]
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[[Category: Everett JK]]
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[[Category: Maglaqui, M.]]
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[[Category: Janjua H]]
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[[Category: Montelione, G T.]]
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[[Category: Maglaqui M]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Pederson, K.]]
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[[Category: Pederson K]]
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[[Category: Prestegard, J H.]]
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[[Category: Prestegard JH]]
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[[Category: Rotshteyn, D J.]]
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[[Category: Rotshteyn DJ]]
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[[Category: Shastry, R.]]
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[[Category: Shastry R]]
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[[Category: Szyperski, T.]]
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[[Category: Szyperski T]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Transport protein]]
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Current revision

Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C

PDB ID 2mj7

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