4i3t
From Proteopedia
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| - | {{STRUCTURE_4i3t| PDB=4i3t | SCENE= }} | ||
| - | ===Structure of phosphonoacetaldehyde dehydrogenase in the apo state=== | ||
| - | {{ABSTRACT_PUBMED_24361046}} | ||
| - | == | + | ==Structure of phosphonoacetaldehyde dehydrogenase in the apo state== |
| - | [[4i3t]] is a 8 chain structure with sequence from [ | + | <StructureSection load='4i3t' size='340' side='right'caption='[[4i3t]], [[Resolution|resolution]] 2.10Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4i3t]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti_1021 Sinorhizobium meliloti 1021]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I3T FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3t OCA], [https://pdbe.org/4i3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i3t RCSB], [https://www.ebi.ac.uk/pdbsum/4i3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i3t ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHNY_RHIME PHNY_RHIME] Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA). Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.<ref>PMID:24361046</ref> | ||
==See Also== | ==See Also== | ||
| - | *[[Aldehyde dehydrogenase|Aldehyde dehydrogenase]] | + | *[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Sinorhizobium meliloti 1021]] |
| - | [[Category: | + | [[Category: Agarwal V]] |
| - | + | [[Category: Nair SK]] | |
| - | + | ||
Current revision
Structure of phosphonoacetaldehyde dehydrogenase in the apo state
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