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1e3m
From Proteopedia
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| - | {{STRUCTURE_1e3m| PDB=1e3m | SCENE= }} | ||
| - | ===The crystal structure of E. coli MutS binding to DNA with a G:T mismatch=== | ||
| - | {{ABSTRACT_PUBMED_11048711}} | ||
| - | == | + | ==The crystal structure of E. coli MutS binding to DNA with a G:T mismatch== |
| - | [[http://www.uniprot.org/uniprot/MUTS_ECOLI MUTS_ECOLI | + | <StructureSection load='1e3m' size='340' side='right'caption='[[1e3m]], [[Resolution|resolution]] 2.20Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1e3m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E3M FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e3m OCA], [https://pdbe.org/1e3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e3m RCSB], [https://www.ebi.ac.uk/pdbsum/1e3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e3m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MUTS_ECOLI MUTS_ECOLI] This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/1e3m_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e3m ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[DNA mismatch repair protein 3D structures|DNA mismatch repair protein 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Escherichia coli]] | |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: De Wind N]] |
| - | [[Category: | + | [[Category: Enzlin JH]] |
| - | [[Category: | + | [[Category: Lamers MH]] |
| - | [[Category: | + | [[Category: Perrakis A]] |
| - | [[Category: | + | [[Category: Sixma TK]] |
| - | [[Category: | + | [[Category: Winterwerp HHK]] |
| - | [[Category: | + | |
| - | + | ||
Current revision
The crystal structure of E. coli MutS binding to DNA with a G:T mismatch
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