This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2jb8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:41, 13 December 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_2jb8| PDB=2jb8 | SCENE= }}
 
-
===Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid===
 
-
==Function==
+
==Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid==
-
[[http://www.uniprot.org/uniprot/CEFE_STRC2 CEFE_STRC2]] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
+
<StructureSection load='2jb8' size='340' side='right'caption='[[2jb8]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[2jb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JB8 FirstGlance]. <br>
-
[[2jb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JB8 OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
-
[[Category: As 4 1611]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HKV:4,5-DIOXOPENTANOIC+ACID'>HKV</scene></td></tr>
-
[[Category: Deacetoxycephalosporin-C synthase]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jb8 OCA], [https://pdbe.org/2jb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jb8 RCSB], [https://www.ebi.ac.uk/pdbsum/2jb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jb8 ProSAT]</span></td></tr>
-
[[Category: Andersson, I.]]
+
</table>
-
[[Category: Carbonera, C.]]
+
== Function ==
-
[[Category: Cicero, G.]]
+
[https://www.uniprot.org/uniprot/CEFE_STRCL CEFE_STRCL] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
-
[[Category: Hajdu, J.]]
+
== Evolutionary Conservation ==
-
[[Category: Ranghino, G.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Valegard, K.]]
+
Check<jmol>
-
[[Category: Antibiotic biosynthesis]]
+
<jmolCheckbox>
-
[[Category: Iron]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jb/2jb8_consurf.spt"</scriptWhenChecked>
-
[[Category: Mononuclear ferrous enzyme]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Oxidoreductase]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Vitamin c]]
+
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jb8 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Streptomyces clavuligerus]]
 +
[[Category: Andersson I]]
 +
[[Category: Carbonera C]]
 +
[[Category: Cicero G]]
 +
[[Category: Hajdu J]]
 +
[[Category: Ranghino G]]
 +
[[Category: Valegard K]]

Current revision

Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid

PDB ID 2jb8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools