2jb8

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{{STRUCTURE_2jb8| PDB=2jb8 | SCENE= }}
 
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===Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid===
 
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==Function==
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==Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid==
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[[http://www.uniprot.org/uniprot/CEFE_STRC2 CEFE_STRC2]] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
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<StructureSection load='2jb8' size='340' side='right'caption='[[2jb8]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[2jb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JB8 FirstGlance]. <br>
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[[2jb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JB8 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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[[Category: As 4 1611]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HKV:4,5-DIOXOPENTANOIC+ACID'>HKV</scene></td></tr>
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[[Category: Deacetoxycephalosporin-C synthase]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jb8 OCA], [https://pdbe.org/2jb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jb8 RCSB], [https://www.ebi.ac.uk/pdbsum/2jb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jb8 ProSAT]</span></td></tr>
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[[Category: Andersson, I.]]
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</table>
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[[Category: Carbonera, C.]]
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== Function ==
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[[Category: Cicero, G.]]
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[https://www.uniprot.org/uniprot/CEFE_STRCL CEFE_STRCL] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
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[[Category: Hajdu, J.]]
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== Evolutionary Conservation ==
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[[Category: Ranghino, G.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Valegard, K.]]
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Check<jmol>
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[[Category: Antibiotic biosynthesis]]
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<jmolCheckbox>
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[[Category: Iron]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jb/2jb8_consurf.spt"</scriptWhenChecked>
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[[Category: Mononuclear ferrous enzyme]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: Oxidoreductase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Vitamin c]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jb8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Streptomyces clavuligerus]]
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[[Category: Andersson I]]
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[[Category: Carbonera C]]
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[[Category: Cicero G]]
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[[Category: Hajdu J]]
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[[Category: Ranghino G]]
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[[Category: Valegard K]]

Current revision

Deacetoxycephalosporin C synthase complexed with 5-hydroxy-4-keto valeric acid

PDB ID 2jb8

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