4hms

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{{STRUCTURE_4hms| PDB=4hms | SCENE= }}
 
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===Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with a second FMN in the substrate binding site===
 
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{{ABSTRACT_PUBMED_23897464}}
 
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==Function==
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==Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with a second FMN in the substrate binding site==
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[[http://www.uniprot.org/uniprot/PHZG_PSEFL PHZG_PSEFL]] Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).
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<StructureSection load='4hms' size='340' side='right'caption='[[4hms]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4hms]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HMS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hms FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hms OCA], [https://pdbe.org/4hms PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hms RCSB], [https://www.ebi.ac.uk/pdbsum/4hms PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hms ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PHZG_PSEFL PHZG_PSEFL] Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).
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==About this Structure==
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==See Also==
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[[4hms]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HMS OCA].
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*[[Pyridoxine 5'-phosphate oxidase|Pyridoxine 5'-phosphate oxidase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023897464</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
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[[Category: Pseudomonas fluorescens]]
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[[Category: Ahuja, E G.]]
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[[Category: Ahuja EG]]
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[[Category: Blankenfeldt, W.]]
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[[Category: Blankenfeldt W]]
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[[Category: Xu, N N.]]
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[[Category: Xu NN]]
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[[Category: Excess fmn]]
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[[Category: Oxidoreductase]]
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[[Category: Substrate mimic]]
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Current revision

Crystal structure of PhzG from Pseudomonas fluorescens 2-79 in complex with a second FMN in the substrate binding site

PDB ID 4hms

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