This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4m0a
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4m0a| PDB=4m0a | SCENE= }} | ||
| - | ===Human DNA Polymerase Mu post-catalytic complex=== | ||
| - | == | + | ==Human DNA Polymerase Mu post-catalytic complex== |
| - | [[http://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN | + | <StructureSection load='4m0a' size='340' side='right'caption='[[4m0a]], [[Resolution|resolution]] 1.85Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4m0a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M0A FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m0a OCA], [https://pdbe.org/4m0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m0a RCSB], [https://www.ebi.ac.uk/pdbsum/4m0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m0a ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN] Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.<ref>PMID:12640116</ref> <ref>PMID:12888504</ref> <ref>PMID:17483519</ref> <ref>PMID:17915942</ref> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] |
| - | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |
| - | == | + | == References == |
| - | <references | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Bebenek | + | </StructureSection> |
| - | [[Category: Kunkel | + | [[Category: Homo sapiens]] |
| - | [[Category: Moon | + | [[Category: Large Structures]] |
| - | [[Category: Pedersen | + | [[Category: Bebenek K]] |
| - | [[Category: Pryor | + | [[Category: Kunkel TA]] |
| - | [[Category: Ramsden | + | [[Category: Moon AF]] |
| - | + | [[Category: Pedersen LC]] | |
| - | + | [[Category: Pryor JM]] | |
| - | + | [[Category: Ramsden DA]] | |
Current revision
Human DNA Polymerase Mu post-catalytic complex
| |||||||||||
Categories: Homo sapiens | Large Structures | Bebenek K | Kunkel TA | Moon AF | Pedersen LC | Pryor JM | Ramsden DA
