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4oa2

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{{STRUCTURE_4oa2| PDB=4oa2 | SCENE= }}
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#REDIRECT [[5lpz]] This PDB entry is obsolete and replaced by 5lpz
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===Crystal structure of the BRI1 kinase domain (865-1196) in complex with ADP from Arabidopsis thaliana===
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==Function==
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[[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref>
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==About this Structure==
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[[4oa2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OA2 OCA].
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Bayliss, R.]]
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[[Category: Bojar, D.]]
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[[Category: Hothorn, M.]]
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[[Category: Martinez, J.]]
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[[Category: Rybin, V.]]
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[[Category: Santiago, J.]]
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[[Category: Atp binding]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Phosphorylation]]
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[[Category: Phosphotransferase]]
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[[Category: Protein binding]]
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[[Category: Transferase]]
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Current revision

  1. REDIRECT 5lpz This PDB entry is obsolete and replaced by 5lpz

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