This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3bo7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="3bo7" size="350" color="white" frame="true" align="right" spinBox="true" caption="3bo7, resolution 2.350&Aring;" /> '''Crystal structure o...)
Current revision (06:34, 3 April 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3bo7.jpg|left|200px]]<br /><applet load="3bo7" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="3bo7, resolution 2.350&Aring;" />
 
-
'''Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136'''<br />
 
-
==About this Structure==
+
==Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136==
-
3BO7 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+202'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+B+202'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+D+202'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+B+203'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+D+203'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+C+202'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+D+204'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+B+204'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+C+203'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+C+204'>BC1</scene>, <scene name='pdbsite=BC2:So4+Binding+Site+For+Residue+B+205'>BC2</scene>, <scene name='pdbsite=BC3:So4+Binding+Site+For+Residue+D+205'>BC3</scene>, <scene name='pdbsite=BC4:So4+Binding+Site+For+Residue+A+203'>BC4</scene>, <scene name='pdbsite=BC5:So4+Binding+Site+For+Residue+A+204'>BC5</scene>, <scene name='pdbsite=BC6:So4+Binding+Site+For+Residue+C+205'>BC6</scene>, <scene name='pdbsite=BC7:So4+Binding+Site+For+Residue+D+206'>BC7</scene>, <scene name='pdbsite=BC8:So4+Binding+Site+For+Residue+A+205'>BC8</scene>, <scene name='pdbsite=BC9:So4+Binding+Site+For+Residue+C+206'>BC9</scene>, <scene name='pdbsite=CC1:So4+Binding+Site+For+Residue+C+207'>CC1</scene>, <scene name='pdbsite=CC2:So4+Binding+Site+For+Residue+A+206'>CC2</scene>, <scene name='pdbsite=CC3:So4+Binding+Site+For+Residue+C+208'>CC3</scene>, <scene name='pdbsite=CC4:Edo+Binding+Site+For+Residue+A+207'>CC4</scene>, <scene name='pdbsite=CC5:Edo+Binding+Site+For+Residue+D+210'>CC5</scene>, <scene name='pdbsite=CC6:Edo+Binding+Site+For+Residue+D+211'>CC6</scene>, <scene name='pdbsite=CC7:Edo+Binding+Site+For+Residue+C+209'>CC7</scene> and <scene name='pdbsite=CC8:Edo+Binding+Site+For+Residue+G+12'>CC8</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO7 OCA].
+
<StructureSection load='3bo7' size='340' side='right'caption='[[3bo7]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-
[[Category: Protein complex]]
+
== Structural highlights ==
-
[[Category: Toxoplasma gondii]]
+
<table><tr><td colspan='2'>[[3bo7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tolypocladium_inflatum Tolypocladium inflatum] and [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BO7 FirstGlance]. <br>
-
[[Category: Arrowsmith, C H.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-
[[Category: Artz, J D.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABA:ALPHA-AMINOBUTYRIC+ACID'>ABA</scene>, <scene name='pdbligand=BMT:4-METHYL-4-[(E)-2-BUTENYL]-4,N-METHYL-THREONINE'>BMT</scene>, <scene name='pdbligand=DAL:D-ALANINE'>DAL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
[[Category: Bochkarev, A.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bo7 OCA], [https://pdbe.org/3bo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bo7 RCSB], [https://www.ebi.ac.uk/pdbsum/3bo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bo7 ProSAT]</span></td></tr>
-
[[Category: Edwards, A M.]]
+
</table>
-
[[Category: Hui, R.]]
+
== Function ==
-
[[Category: Khuu, C.]]
+
[https://www.uniprot.org/uniprot/D0VWS5_TOXGO D0VWS5_TOXGO] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).[RuleBase:RU004223]
-
[[Category: Kozieradzki, I.]]
+
== Evolutionary Conservation ==
-
[[Category: Lew, J.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Lin, Y H.]]
+
Check<jmol>
-
[[Category: SGC, Structural Genomics Consortium.]]
+
<jmolCheckbox>
-
[[Category: Schapira, M.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bo/3bo7_consurf.spt"</scriptWhenChecked>
-
[[Category: Sun, X.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Weigelt, J.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Wernimont, A K.]]
+
</jmolCheckbox>
-
[[Category: Xiao, T.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bo7 ConSurf].
-
[[Category: Zhao, Y.]]
+
<div style="clear:both"></div>
-
[[Category: EDO]]
+
-
[[Category: SO4]]
+
-
[[Category: cyclosporin a]]
+
-
[[Category: isomerase]]
+
-
[[Category: large cyclophilin]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomics]]
+
-
[[Category: structural genomics consortium]]
+
-
[[Category: toxoplasma gondii]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:06:51 2008''
+
==See Also==
 +
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Tolypocladium inflatum]]
 +
[[Category: Toxoplasma gondii]]
 +
[[Category: Arrowsmith CH]]
 +
[[Category: Artz JD]]
 +
[[Category: Bochkarev A]]
 +
[[Category: Edwards AM]]
 +
[[Category: Hui R]]
 +
[[Category: Khuu C]]
 +
[[Category: Kozieradzki I]]
 +
[[Category: Lew J]]
 +
[[Category: Lin YH]]
 +
[[Category: Schapira M]]
 +
[[Category: Sun X]]
 +
[[Category: Weigelt J]]
 +
[[Category: Wernimont AK]]
 +
[[Category: Xiao T]]
 +
[[Category: Zhao Y]]

Current revision

Crystal structure of Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, 541.m00136

PDB ID 3bo7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3bo7"
Personal tools