4lq3

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{{STRUCTURE_4lq3| PDB=4lq3 | SCENE= }}
 
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===Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS===
 
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{{ABSTRACT_PUBMED_24316032}}
 
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==About this Structure==
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==Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS==
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[[4lq3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ3 OCA].
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<StructureSection load='4lq3' size='340' side='right'caption='[[4lq3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lq3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Norovirus Norovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LQ3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=20V:3-[(E)-{4-FORMYL-5-HYDROXY-6-METHYL-3-[(PHOSPHONOOXY)METHYL]PYRIDIN-2-YL}DIAZENYL]-7-NITRONAPHTHALENE-1,5-DISULFONIC+ACID'>20V</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq3 OCA], [https://pdbe.org/4lq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lq3 RCSB], [https://www.ebi.ac.uk/pdbsum/4lq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q2N379_9CALI Q2N379_9CALI]
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==Reference==
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==See Also==
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<ref group="xtra">PMID:024316032</ref><references group="xtra"/><references/>
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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[[Category: Mastrangelo, E.]]
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__TOC__
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[[Category: Milani, M.]]
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</StructureSection>
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[[Category: Romina, C.]]
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[[Category: Large Structures]]
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[[Category: Tarantino, D.]]
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[[Category: Norovirus]]
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[[Category: Rdrp-inhibotir complex]]
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[[Category: Croci R]]
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[[Category: Rna-dependent-rna-polymerase]]
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[[Category: Mastrangelo E]]
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[[Category: Viral protein-replication inhibitor-rna complex]]
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[[Category: Milani M]]
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[[Category: Tarantino D]]

Current revision

Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS

PDB ID 4lq3

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