4cd3

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{{STRUCTURE_4cd3| PDB=4cd3 | SCENE= }}
 
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===RnNTPDase2 X4 variant in complex with PSB-071===
 
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{{ABSTRACT_PUBMED_24462745}}
 
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==Function==
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==RnNTPDase2 X4 variant in complex with PSB-071==
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[[http://www.uniprot.org/uniprot/ENTP2_RAT ENTP2_RAT]] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
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<StructureSection load='4cd3' size='340' side='right'caption='[[4cd3]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4cd3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CD3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8E9:1-AMINO-4-(3-METHYLPHENYL)AMINO-9,10-DIOXO-9,10-DIHYDROANTHRACENE-2-SULFONATE'>8E9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cd3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cd3 OCA], [https://pdbe.org/4cd3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cd3 RCSB], [https://www.ebi.ac.uk/pdbsum/4cd3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cd3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[https://www.uniprot.org/uniprot/ENTP2_RAT ENTP2_RAT]] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
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==About this Structure==
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==See Also==
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[[4cd3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD3 OCA].
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*[[Ectonucleoside triphosphate diphosphohydrolase|Ectonucleoside triphosphate diphosphohydrolase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024462745</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Schaefer, P.]]
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[[Category: Rattus norvegicus]]
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[[Category: Straeter, N.]]
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[[Category: Schaefer P]]
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[[Category: Zebisch, M.]]
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[[Category: Straeter N]]
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[[Category: Apyrase]]
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[[Category: Zebisch M]]
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[[Category: Atpase]]
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[[Category: Drug design]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Ntpdase]]
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[[Category: Purinergic signalling]]
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Current revision

RnNTPDase2 X4 variant in complex with PSB-071

PDB ID 4cd3

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