4nyn
From Proteopedia
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| - | {{STRUCTURE_4nyn| PDB=4nyn | SCENE= }} | ||
| - | ===Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1=== | ||
| - | == | + | ==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1== |
| - | [[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA | + | <StructureSection load='4nyn' size='340' side='right'caption='[[4nyn]], [[Resolution|resolution]] 1.41Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4nyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_NRC-1 Halobacterium salinarum NRC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NYN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyn OCA], [https://pdbe.org/4nyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nyn RCSB], [https://www.ebi.ac.uk/pdbsum/4nyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nyn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | <references | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Angkawidjaja | + | [[Category: Halobacterium salinarum NRC-1]] |
| - | [[Category: Kanaya | + | [[Category: Large Structures]] |
| - | [[Category: Koga | + | [[Category: Angkawidjaja C]] |
| - | [[Category: You | + | [[Category: Kanaya S]] |
| - | + | [[Category: Koga Y]] | |
| - | + | [[Category: You DJ]] | |
Current revision
Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
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