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1gm7
From Proteopedia
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| - | {{STRUCTURE_1gm7| PDB=1gm7 | SCENE= }} | ||
| - | ===Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism=== | ||
| - | {{ABSTRACT_PUBMED_11601852}} | ||
| - | == | + | ==Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism== |
| - | [[1gm7]] is a 2 chain structure with sequence from [ | + | <StructureSection load='1gm7' size='340' side='right'caption='[[1gm7]], [[Resolution|resolution]] 1.45Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1gm7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GM7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gm7 OCA], [https://pdbe.org/1gm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gm7 RCSB], [https://www.ebi.ac.uk/pdbsum/1gm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gm7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAC_ECOLX PAC_ECOLX] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/1gm7_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gm7 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Penicillin acylase|Penicillin acylase]] | *[[Penicillin acylase|Penicillin acylase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Escherichia coli]] | |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Brannigan JA]] |
| - | [[Category: Brannigan | + | [[Category: Dodson GG]] |
| - | [[Category: Dodson | + | [[Category: McVey CE]] |
| - | [[Category: McVey | + | [[Category: Walsh MA]] |
| - | [[Category: Walsh | + | [[Category: Wilson KS]] |
| - | [[Category: Wilson | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
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