4n7g

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{{STRUCTURE_4n7g| PDB=4n7g | SCENE= }}
 
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===Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS===
 
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{{ABSTRACT_PUBMED_24504455}}
 
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==Function==
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==Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS==
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[[http://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref>
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<StructureSection load='4n7g' size='340' side='right'caption='[[4n7g]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4n7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N7G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n7g OCA], [https://pdbe.org/4n7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n7g RCSB], [https://www.ebi.ac.uk/pdbsum/4n7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n7g ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref>
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==About this Structure==
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==See Also==
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[[4n7g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7G OCA].
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*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:024504455</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Bier, D.]]
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</StructureSection>
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[[Category: Glas, A.]]
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[[Category: Homo sapiens]]
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[[Category: Grossmann, T.]]
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[[Category: Large Structures]]
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[[Category: Hahne, G.]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Ottmann, C.]]
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[[Category: Bier D]]
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[[Category: 14-3-3]]
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[[Category: Glas A]]
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[[Category: Adaptor protein]]
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[[Category: Grossmann T]]
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[[Category: Cross-link]]
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[[Category: Hahne G]]
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[[Category: Protein-protein interaction]]
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[[Category: Ottmann C]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS

PDB ID 4n7g

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