4nyh

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{{STRUCTURE_4nyh| PDB=4nyh | SCENE= }}
 
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===Orthorhombic crystal form of pir1 dual specificity phosphatase core===
 
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{{ABSTRACT_PUBMED_24447265}}
 
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==Function==
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==Orthorhombic crystal form of pir1 dual specificity phosphatase core==
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[[http://www.uniprot.org/uniprot/DUS11_HUMAN DUS11_HUMAN]] Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism.<ref>PMID:9685386</ref>
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<StructureSection load='4nyh' size='340' side='right'caption='[[4nyh]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4nyh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NYH FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nyh OCA], [https://pdbe.org/4nyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nyh RCSB], [https://www.ebi.ac.uk/pdbsum/4nyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nyh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DUS11_HUMAN DUS11_HUMAN] Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism.<ref>PMID:9685386</ref>
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==About this Structure==
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==See Also==
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[[4nyh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYH OCA].
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*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:024447265</ref><references group="xtra"/><references/>
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__TOC__
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[[Category: Cingolani, G.]]
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</StructureSection>
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[[Category: Lokareddy, R K.]]
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[[Category: Homo sapiens]]
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[[Category: Sankhala, R S.]]
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[[Category: Large Structures]]
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[[Category: Dephosphorylation]]
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[[Category: Cingolani G]]
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[[Category: Dual specificity phosphatase]]
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[[Category: Lokareddy RK]]
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[[Category: Hydrolase]]
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[[Category: Sankhala RS]]
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[[Category: Nucleus]]
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[[Category: P-loop]]
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[[Category: Protein tyrosine phosphatase]]
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[[Category: Rna-rnp complex-1]]
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Current revision

Orthorhombic crystal form of pir1 dual specificity phosphatase core

PDB ID 4nyh

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