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| - | {{STRUCTURE_4oa6| PDB=4oa6 | SCENE= }}
| + | #REDIRECT [[5lpw]] This PDB entry is obsolete and replaced by 5lpw |
| - | ===Crystal structure of the apo-BRI1 kinase domain (865-1160)===
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| - | {{ABSTRACT_PUBMED_24461462}}
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| - | ==Function==
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| - | [[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref> | + | |
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| - | ==About this Structure==
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| - | [[4oa6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OA6 OCA].
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| - | ==Reference==
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| - | <ref group="xtra">PMID:024461462</ref><references group="xtra"/><references/>
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| - | [[Category: Bayliss, R.]]
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| - | [[Category: Bojar, D.]]
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| - | [[Category: Hothorn, M.]]
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| - | [[Category: Martinez, J.]]
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| - | [[Category: Rybin, V.]]
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| - | [[Category: Santiago, J.]]
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| - | [[Category: Atp binding]]
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| - | [[Category: Kinase]]
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| - | [[Category: Membrane]]
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| - | [[Category: Phosphorylation]]
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| - | [[Category: Phosphotransferase]]
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| - | [[Category: Protein binding]]
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| - | [[Category: Transferase]]
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