4gon
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| - | {{STRUCTURE_4gon| PDB=4gon | SCENE= }} | ||
| - | ===Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM=== | ||
| - | == | + | ==Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM== |
| - | [[http://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI | + | <StructureSection load='4gon' size='340' side='right'caption='[[4gon]], [[Resolution|resolution]] 2.72Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gon]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GON FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.72Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0Y1:5-{[(3S)-3-AMINO-3-CARBOXYPROPYL][2-(1H-INDOL-3-YL)ETHYL]AMINO}-5-DEOXYADENOSINE'>0Y1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gon OCA], [https://pdbe.org/4gon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gon RCSB], [https://www.ebi.ac.uk/pdbsum/4gon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gon ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DMA_ECOLI DMA_ECOLI] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication. | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[DNA adenine methylase|DNA adenine methylase]] |
| - | [[Category: | + | *[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Escherichia coli K-12]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Harmer JE]] | ||
| + | [[Category: Roach PL]] | ||
Current revision
Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Indole Aza-SAM
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