2mlr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Alpha-face== | |
| + | <StructureSection load='2mlr' size='340' side='right'caption='[[2mlr]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2mlr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLR FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mlr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mlr OCA], [https://pdbe.org/2mlr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mlr RCSB], [https://www.ebi.ac.uk/pdbsum/2mlr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mlr ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MMP12_HUMAN MMP12_HUMAN] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3. | ||
| - | + | ==See Also== | |
| - | + | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Fulcher YG]] | ||
| + | [[Category: Koppisetti RK]] | ||
| + | [[Category: Lenoir M]] | ||
| + | [[Category: Overduin M]] | ||
| + | [[Category: Prior SH]] | ||
| + | [[Category: Van Doren SR]] | ||
Current revision
Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Alpha-face
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