4msu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:28, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4msu| PDB=4msu | SCENE= }}
 
-
===Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate===
 
-
{{ABSTRACT_PUBMED_24405172}}
 
-
==Function==
+
==Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate==
-
[[http://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN]] Inhibits glucokinase by forming an inactive complex with this enzyme.
+
<StructureSection load='4msu' size='340' side='right'caption='[[4msu]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4msu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MSU FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2EU:1,1,1,3,3,3-HEXAFLUORO-2-{4-[4-(THIOPHEN-2-YLSULFONYL)PIPERAZIN-1-YL]PHENYL}PROPAN-2-OL'>2EU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4msu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4msu OCA], [https://pdbe.org/4msu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4msu RCSB], [https://www.ebi.ac.uk/pdbsum/4msu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4msu ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.
-
==About this Structure==
+
==See Also==
-
[[4msu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MSU OCA].
+
*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:024405172</ref><references group="xtra"/><references/>
+
[[Category: Homo sapiens]]
-
[[Category: Andrews, K L.]]
+
[[Category: Large Structures]]
-
[[Category: Ashton, K S.]]
+
[[Category: Andrews KL]]
-
[[Category: Bryan, M C.]]
+
[[Category: Ashton KS]]
-
[[Category: Chen, J.]]
+
[[Category: Bryan MC]]
-
[[Category: Chen, K.]]
+
[[Category: Chen J]]
-
[[Category: Chen, M.]]
+
[[Category: Chen K]]
-
[[Category: Chmait, S.]]
+
[[Category: Chen M]]
-
[[Category: Croghan, M.]]
+
[[Category: Chmait S]]
-
[[Category: Cupples, R.]]
+
[[Category: Croghan M]]
-
[[Category: Fotsch, C.]]
+
[[Category: Cupples R]]
-
[[Category: Hale, C.]]
+
[[Category: Fotsch C]]
-
[[Category: Helmering, J.]]
+
[[Category: Hale C]]
-
[[Category: Jean, D J.St.]]
+
[[Category: Helmering J]]
-
[[Category: Jordan, S R.]]
+
[[Category: Jordan SR]]
-
[[Category: Kurzeja, R J.]]
+
[[Category: Kurzeja RJ]]
-
[[Category: Lloyd, D J.]]
+
[[Category: Lloyd DJ]]
-
[[Category: Michelsen, K.]]
+
[[Category: Michelsen K]]
-
[[Category: Pennington, L D.]]
+
[[Category: Pennington LD]]
-
[[Category: Poon, S F.]]
+
[[Category: Poon SF]]
-
[[Category: Sivits, G.]]
+
[[Category: Sivits G]]
-
[[Category: Van, G.]]
+
[[Category: St Jean DJ]]
-
[[Category: Vonderfecht, S L.]]
+
[[Category: Van G]]
-
[[Category: Wahl, R C.]]
+
[[Category: Vonderfecht SL]]
-
[[Category: Zhang, J.]]
+
[[Category: Wahl RC]]
-
[[Category: Glucokinase]]
+
[[Category: Zhang J]]
-
[[Category: Phospho-fructose]]
+
-
[[Category: Regulatory protein]]
+
-
[[Category: Sis domain]]
+
-
[[Category: Sugar binding protein]]
+

Current revision

Human GKRP bound to AMG-6861 and Sorbitol-6-phosphate

PDB ID 4msu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4msu"
Personal tools