3g1l

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:51, 21 February 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3g1l| PDB=3g1l | SCENE= }}
 
-
===EthR from Mycobacterium tuberculosis in complex with compound BDM14744===
 
-
{{ABSTRACT_PUBMED_19412174}}
 
-
==Function==
+
==EthR from Mycobacterium tuberculosis in complex with compound BDM14744==
-
[[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
+
<StructureSection load='3g1l' size='340' side='right'caption='[[3g1l]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3g1l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G1L FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RF2:3-(4-FLUOROPHENYL)-5-PHENYL-4H-1,2,4-TRIAZOLE'>RF2</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g1l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g1l OCA], [https://pdbe.org/3g1l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g1l RCSB], [https://www.ebi.ac.uk/pdbsum/3g1l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g1l ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g1/3g1l_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g1l ConSurf].
 +
<div style="clear:both"></div>
-
==About this Structure==
+
==See Also==
-
[[3g1l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1L OCA].
+
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:019412174</ref><references group="xtra"/><references/>
+
__TOC__
-
[[Category: Aumercier, M.]]
+
</StructureSection>
-
[[Category: Baulard, A R.]]
+
[[Category: Large Structures]]
-
[[Category: Bifani, P.]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Carette, X.]]
+
[[Category: Aumercier M]]
-
[[Category: Delcroix, G.]]
+
[[Category: Baulard AR]]
-
[[Category: Deprez, B.]]
+
[[Category: Bifani P]]
-
[[Category: Deprez-Poulain, R.]]
+
[[Category: Carette X]]
-
[[Category: Desroses, M.]]
+
[[Category: Delcroix G]]
-
[[Category: Dirie, B.]]
+
[[Category: Deprez B]]
-
[[Category: Frenois, F.]]
+
[[Category: Deprez-Poulain R]]
-
[[Category: Leroux, F.]]
+
[[Category: Desroses M]]
-
[[Category: Locht, C.]]
+
[[Category: Dirie B]]
-
[[Category: Mathys, V.]]
+
[[Category: Frenois F]]
-
[[Category: Singhal, A.]]
+
[[Category: Leroux F]]
-
[[Category: Villeret, V.]]
+
[[Category: Locht C]]
-
[[Category: Willand, N.]]
+
[[Category: Mathys V]]
-
[[Category: Willery, E.]]
+
[[Category: Singhal A]]
-
[[Category: Dna-binding]]
+
[[Category: Villeret V]]
-
[[Category: Tetr family]]
+
[[Category: Willand N]]
-
[[Category: Transcription]]
+
[[Category: Willery E]]
-
[[Category: Transcription regulation]]
+

Current revision

EthR from Mycobacterium tuberculosis in complex with compound BDM14744

PDB ID 3g1l

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3g1l"
Personal tools