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4orf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==cAMP-binding acyltransferase from Mycobacterium smegmatis, mutant R95K== | |
| - | + | <StructureSection load='4orf' size='340' side='right'caption='[[4orf]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4orf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ORF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ORF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4orf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4orf OCA], [https://pdbe.org/4orf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4orf RCSB], [https://www.ebi.ac.uk/pdbsum/4orf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4orf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PAT_MYCS2 PAT_MYCS2] Catalyzes specifically the acetylation of the epsilon-amino group of a highly conserved lysine residue in acetyl-CoA synthetase (ACS) and of the universal stress protein (USP) MSMEG_4207. Acetylation results in the inactivation of ACS activity and could be important for mycobacteria to adjust to environmental changes.<ref>PMID:20507997</ref> <ref>PMID:21627103</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycolicibacterium smegmatis MC2 155]] | ||
| + | [[Category: Podobnik M]] | ||
| + | [[Category: Rebolj K]] | ||
| + | [[Category: Visweswariah SS]] | ||
Current revision
cAMP-binding acyltransferase from Mycobacterium smegmatis, mutant R95K
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