3whb

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{{STRUCTURE_3whb| PDB=3whb | SCENE= }}
 
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===Crystal structure of FadR from Bacillus subtilis, a transcriptional regulator involved in the regulation of fatty acid degradation===
 
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{{ABSTRACT_PUBMED_24356978}}
 
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==Function==
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==Crystal structure of FadR from Bacillus subtilis, a transcriptional regulator involved in the regulation of fatty acid degradation==
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[[http://www.uniprot.org/uniprot/FADR_BACSU FADR_BACSU]] Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.
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<StructureSection load='3whb' size='340' side='right'caption='[[3whb]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3whb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WHB FirstGlance]. <br>
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[[3whb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WHB OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCC:DODECYL-COA'>DCC</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3whb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3whb OCA], [https://pdbe.org/3whb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3whb RCSB], [https://www.ebi.ac.uk/pdbsum/3whb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3whb ProSAT]</span></td></tr>
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<ref group="xtra">PMID:024356978</ref><references group="xtra"/><references/>
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</table>
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[[Category: Fujihashi, M.]]
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== Function ==
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[[Category: Miki, K.]]
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[https://www.uniprot.org/uniprot/FADR_BACSU FADR_BACSU] Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.
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[[Category: Nakatani, T.]]
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__TOC__
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[[Category: Fatty acid degradation]]
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</StructureSection>
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[[Category: Transcription]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Transcriptional regulator]]
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[[Category: Large Structures]]
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[[Category: Fujihashi M]]
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[[Category: Miki K]]
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[[Category: Nakatani T]]

Current revision

Crystal structure of FadR from Bacillus subtilis, a transcriptional regulator involved in the regulation of fatty acid degradation

PDB ID 3whb

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