4lzg

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{{STRUCTURE_4lzg| PDB=4lzg | SCENE= }}
 
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===Binary complex of human DNA Polymerase Mu with DNA===
 
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{{ABSTRACT_PUBMED_24487959}}
 
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==Function==
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==Binary complex of human DNA Polymerase Mu with DNA==
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[[http://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN]] Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.<ref>PMID:12640116</ref> <ref>PMID:12888504</ref> <ref>PMID:17483519</ref> <ref>PMID:17915942</ref>
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<StructureSection load='4lzg' size='340' side='right'caption='[[4lzg]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4lzg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LZG FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.599&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lzg OCA], [https://pdbe.org/4lzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lzg RCSB], [https://www.ebi.ac.uk/pdbsum/4lzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lzg ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN] Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.<ref>PMID:12640116</ref> <ref>PMID:12888504</ref> <ref>PMID:17483519</ref> <ref>PMID:17915942</ref>
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==About this Structure==
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==See Also==
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[[4lzg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LZG OCA].
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:024487959</ref><references group="xtra"/><references/>
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<references/>
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[[Category: DNA-directed DNA polymerase]]
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__TOC__
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[[Category: Bebenek, K.]]
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</StructureSection>
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[[Category: Kunkel, T A.]]
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[[Category: Homo sapiens]]
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[[Category: Moon, A F.]]
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[[Category: Large Structures]]
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[[Category: Pedersen, L C.]]
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[[Category: Bebenek K]]
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[[Category: Pryor, J M.]]
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[[Category: Kunkel TA]]
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[[Category: Ramsden, D A.]]
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[[Category: Moon AF]]
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[[Category: Dna break repair]]
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[[Category: Pedersen LC]]
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[[Category: Polymerase]]
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[[Category: Pryor JM]]
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[[Category: Transferase-dna complex]]
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[[Category: Ramsden DA]]

Current revision

Binary complex of human DNA Polymerase Mu with DNA

PDB ID 4lzg

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