4nxv

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{{STRUCTURE_4nxv| PDB=4nxv | SCENE= }}
 
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===Crystal structure of the cytosolic domain of human MiD51===
 
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{{ABSTRACT_PUBMED_24515348}}
 
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==Function==
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==Crystal structure of the cytosolic domain of human MiD51==
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[[http://www.uniprot.org/uniprot/MID51_HUMAN MID51_HUMAN]] Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins.<ref>PMID:21508961</ref> <ref>PMID:21701560</ref> <ref>PMID:23921378</ref> <ref>PMID:23283981</ref> <ref>PMID:23530241</ref>
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<StructureSection load='4nxv' size='340' side='right'caption='[[4nxv]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[4nxv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NXV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NXV FirstGlance]. <br>
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[[4nxv]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NXV OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nxv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nxv OCA], [https://pdbe.org/4nxv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nxv RCSB], [https://www.ebi.ac.uk/pdbsum/4nxv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nxv ProSAT]</span></td></tr>
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<ref group="xtra">PMID:024515348</ref><references group="xtra"/><references/>
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</table>
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[[Category: Kvansakul, M.]]
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== Function ==
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[[Category: Richter, V.]]
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[https://www.uniprot.org/uniprot/MID51_HUMAN MID51_HUMAN] Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins.<ref>PMID:21508961</ref> <ref>PMID:21701560</ref> <ref>PMID:23921378</ref> <ref>PMID:23283981</ref> <ref>PMID:23530241</ref>
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[[Category: Ryan, M T.]]
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== References ==
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[[Category: Adp]]
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<references/>
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[[Category: Gdp]]
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__TOC__
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[[Category: Membrane-anchored]]
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</StructureSection>
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[[Category: Mitochondria]]
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[[Category: Homo sapiens]]
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[[Category: Mitochondrial fission]]
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[[Category: Large Structures]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Kvansakul M]]
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[[Category: Protein-nucleotide complex]]
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[[Category: Richter V]]
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[[Category: Protein-protein interaction]]
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[[Category: Ryan MT]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the cytosolic domain of human MiD51

PDB ID 4nxv

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