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4hpd

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{{STRUCTURE_4hpd| PDB=4hpd | SCENE= }}
 
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===Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with homocysteine at pH 7.4===
 
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{{ABSTRACT_PUBMED_23474537}}
 
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==Function==
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==Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with homocysteine at pH 7.4==
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[[http://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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<StructureSection load='4hpd' size='340' side='right'caption='[[4hpd]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4hpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HPD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpd OCA], [https://pdbe.org/4hpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hpd RCSB], [https://www.ebi.ac.uk/pdbsum/4hpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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==About this Structure==
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==See Also==
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[[4hpd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPD OCA].
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*[[Nitrophorin|Nitrophorin]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:023474537</ref><references group="xtra"/><references/>
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[[Category: Large Structures]]
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[[Category: Rhopr]]
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[[Category: Rhodnius prolixus]]
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[[Category: Knipp, M.]]
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[[Category: Knipp M]]
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[[Category: Nishikawa, K.]]
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[[Category: Nishikawa K]]
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[[Category: Ogata, H.]]
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[[Category: Ogata H]]
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[[Category: Heme]]
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[[Category: Lipocalin]]
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[[Category: Metal binding protein]]
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[[Category: Nitrophorin]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of Nitrophorin 4 from Rhodnius prolixus Complexed with homocysteine at pH 7.4

PDB ID 4hpd

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