4l9p

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{{STRUCTURE_4l9p| PDB=4l9p | SCENE= }}
 
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===Crystal structure of Aspergillus fumigatus protein farnesyltransferase complexed with the FII analog, FPT-II, and the KCVVM peptide===
 
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{{ABSTRACT_PUBMED_24347326}}
 
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==About this Structure==
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==Crystal structure of Aspergillus fumigatus protein farnesyltransferase complexed with the FII analog, FPT-II, and the KCVVM peptide==
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[[4l9p]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9P OCA].
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<StructureSection load='4l9p' size='340' side='right'caption='[[4l9p]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4l9p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_fumigatus_Af293 Aspergillus fumigatus Af293]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L9P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FII:[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC+ACID'>FII</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l9p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9p OCA], [https://pdbe.org/4l9p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l9p RCSB], [https://www.ebi.ac.uk/pdbsum/4l9p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l9p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q4WP27_ASPFU Q4WP27_ASPFU]
==See Also==
==See Also==
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*[[Farnesyltransferase|Farnesyltransferase]]
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*[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:024347326</ref><references group="xtra"/><references/>
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[[Category: Aspergillus fumigatus Af293]]
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[[Category: Protein farnesyltransferase]]
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[[Category: Large Structures]]
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[[Category: Beese, L S.]]
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[[Category: Beese LS]]
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[[Category: Hast, M A.]]
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[[Category: Hast MA]]
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[[Category: Mabanglo, M F.]]
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[[Category: Mabanglo MF]]
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[[Category: Caax farnesyltransferase]]
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[[Category: Isoprenoid and caax protein/peptide substrate]]
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[[Category: Ternary complex with isoprenoid and caax peptide substrate]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Aspergillus fumigatus protein farnesyltransferase complexed with the FII analog, FPT-II, and the KCVVM peptide

PDB ID 4l9p

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