4ip9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:58, 1 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4ip9| PDB=4ip9 | SCENE= }}
 
-
===Structure of native human serum amyloid A1===
 
-
==Disease==
+
==Structure of native human serum amyloid A1==
-
[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.
+
<StructureSection load='4ip9' size='340' side='right'caption='[[4ip9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[4ip9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IP9 FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN]] Major acute phase reactant. Apolipoprotein of the HDL complex.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P4C:O-ACETALDEHYDYL-HEXAETHYLENE+GLYCOL'>P4C</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ip9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ip9 OCA], [https://pdbe.org/4ip9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ip9 RCSB], [https://www.ebi.ac.uk/pdbsum/4ip9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ip9 ProSAT]</span></td></tr>
-
[[4ip9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IP9 OCA].
+
</table>
-
[[Category: Lu, J.]]
+
== Disease ==
-
[[Category: Sun, P D]]
+
[https://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN] Secondary amyloidosis. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer.
-
[[Category: Double layer hexameric structure]]
+
== Function ==
-
[[Category: High density lipoprotein]]
+
[https://www.uniprot.org/uniprot/SAA1_HUMAN SAA1_HUMAN] Major acute phase reactant. Apolipoprotein of the HDL complex.
-
[[Category: Human serum]]
+
__TOC__
-
[[Category: Protein binding]]
+
</StructureSection>
-
[[Category: Secondary amyloid]]
+
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Lu J]]
 +
[[Category: Sun PD]]

Current revision

Structure of native human serum amyloid A1

PDB ID 4ip9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ip9"
Personal tools