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8lyz

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[[Image:8lyz.gif|left|200px]]<br /><applet load="8lyz" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="8lyz, resolution 2.5&Aring;" />
 
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'''AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME'''<br />
 
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==About this Structure==
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==AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME==
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8LYZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8LYZ OCA].
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<StructureSection load='8lyz' size='340' side='right' caption='[[8lyz]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8lyz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8LYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=8LYZ FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=8lyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8lyz OCA], [http://pdbe.org/8lyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=8lyz RCSB], [http://www.ebi.ac.uk/pdbsum/8lyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=8lyz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ly/8lyz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=8lyz ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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An x-ray study of the structure and binding properties of iodine-inactivated lysozyme., Beddell CR, Blake CC, Oatley SJ, J Mol Biol. 1975 Oct 5;97(4):643-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1185784 1185784]
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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[[Category: Gallus gallus]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Chick]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
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[[Category: Single protein]]
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[[Category: Beddell, C R]]
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[[Category: Beddell, C R.]]
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[[Category: Blake, C C.F]]
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[[Category: Blake, C C.F.]]
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[[Category: Oatley, S J]]
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[[Category: Oatley, S J.]]
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[[Category: hydrolase (o-glycosyl)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:18:15 2008''
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Current revision

AN X-RAY STUDY OF THE STRUCTURE AND BINDING PROPERTIES OF IODINE-INACTIVATED LYSOZYME

8lyz, resolution 2.50Å

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