2rf3
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| - | [[Image:2rf3.jpg|left|200px]]<br /><applet load="2rf3" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2rf3, resolution 1.75Å" /> | ||
| - | '''Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles'''<br /> | ||
| - | == | + | ==Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles== |
| + | <StructureSection load='2rf3' size='340' side='right'caption='[[2rf3]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2rf3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RF3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene>, <scene name='pdbligand=TCY:(2R,3AS,4AR,5AR,5BS)-2-(6-AMINO-9H-PURIN-9-YL)-3A-HYDROXYHEXAHYDROCYCLOPROPA[4,5]CYCLOPENTA[1,2-B]FURAN-5A(4H)-YL+DIHYDROGEN+PHOSPHATE'>TCY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rf3 OCA], [https://pdbe.org/2rf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rf3 RCSB], [https://www.ebi.ac.uk/pdbsum/2rf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rf3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases. | The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases. | ||
| - | + | Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.,Pallan PS, Ittig D, Heroux A, Wawrzak Z, Leumann CJ, Egli M Chem Commun (Camb). 2008 Feb 21;(7):883-5. Epub 2007 Dec 21. PMID:18253536<ref>PMID:18253536</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: | + | <div class="pdbe-citations 2rf3" style="background-color:#fffaf0;"></div> |
| - | [[Category: Egli | + | == References == |
| - | [[Category: Heroux | + | <references/> |
| - | [[Category: Ittig | + | __TOC__ |
| - | [[Category: Leumann | + | </StructureSection> |
| - | [[Category: Pallan | + | [[Category: Large Structures]] |
| - | [[Category: Wawrzak | + | [[Category: Egli M]] |
| - | + | [[Category: Heroux A]] | |
| - | + | [[Category: Ittig D]] | |
| - | + | [[Category: Leumann CJ]] | |
| - | + | [[Category: Pallan PS]] | |
| - | + | [[Category: Wawrzak Z]] | |
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Current revision
Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles
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Categories: Large Structures | Egli M | Heroux A | Ittig D | Leumann CJ | Pallan PS | Wawrzak Z
