3wdm

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{{STRUCTURE_3wdm| PDB=3wdm | SCENE= }}
 
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===Crystal structure of 4-phosphopantoate-beta-alanine ligase from Thermococcus kodakarensis===
 
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{{ABSTRACT_PUBMED_24638914}}
 
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==Function==
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==Crystal structure of 4-phosphopantoate-beta-alanine ligase from Thermococcus kodakarensis==
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[[http://www.uniprot.org/uniprot/PPS_THEKO PPS_THEKO]] Catalyzes the conversion of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway. Cannot use (R)-pantoate as substrate and thus does not display pantothenate synthetase (PS) activity.
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<StructureSection load='3wdm' size='340' side='right'caption='[[3wdm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3wdm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WDM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WDM FirstGlance]. <br>
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[[3wdm]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WDM OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wdm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wdm OCA], [https://pdbe.org/3wdm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wdm RCSB], [https://www.ebi.ac.uk/pdbsum/3wdm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wdm ProSAT]</span></td></tr>
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<ref group="xtra">PMID:024638914</ref><references group="xtra"/><references/>
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</table>
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[[Category: 4-phosphopantoate--beta-alanine ligase]]
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== Function ==
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[[Category: Atomi, H.]]
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[https://www.uniprot.org/uniprot/PPS_THEKO PPS_THEKO] Catalyzes the conversion of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway. Cannot use (R)-pantoate as substrate and thus does not display pantothenate synthetase (PS) activity.
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[[Category: Imanaka, T.]]
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__TOC__
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[[Category: Ishibashi, T.]]
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</StructureSection>
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[[Category: Kishimoto, A.]]
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[[Category: Large Structures]]
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[[Category: Kita, A.]]
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[[Category: Thermococcus kodakarensis KOD1]]
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[[Category: Miki, K.]]
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[[Category: Atomi H]]
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[[Category: Tomita, H.]]
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[[Category: Imanaka T]]
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[[Category: Yokooji, Y.]]
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[[Category: Ishibashi T]]
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[[Category: Ligase]]
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[[Category: Kishimoto A]]
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[[Category: Kita A]]
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[[Category: Miki K]]
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[[Category: Tomita H]]
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[[Category: Yokooji Y]]

Current revision

Crystal structure of 4-phosphopantoate-beta-alanine ligase from Thermococcus kodakarensis

PDB ID 3wdm

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