4njt

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{{STRUCTURE_4njt| PDB=4njt | SCENE= }}
 
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===Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir===
 
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==About this Structure==
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==Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir==
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[[4njt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJT OCA].
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<StructureSection load='4njt' size='340' side='right'caption='[[4njt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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[[Category: Chang, S B.]]
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== Structural highlights ==
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[[Category: Das, D.]]
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<table><tr><td colspan='2'>[[4njt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NJT FirstGlance]. <br>
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[[Category: Garimella, H.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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[[Category: Ghosh, A K.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene></td></tr>
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[[Category: Kaufman, J D.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4njt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4njt OCA], [https://pdbe.org/4njt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4njt RCSB], [https://www.ebi.ac.uk/pdbsum/4njt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4njt ProSAT]</span></td></tr>
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[[Category: Mitsuya, H.]]
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</table>
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[[Category: Wingfield, P T.]]
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== Function ==
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[[Category: Yedidi, R S.]]
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[https://www.uniprot.org/uniprot/Q9J006_9HIV1 Q9J006_9HIV1]
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[[Category: Darunavir]]
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[[Category: Hiv-1 protease]]
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==See Also==
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
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[[Category: Multidrug-resistance]]
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__TOC__
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[[Category: Non-peptidic inhibitor]]
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</StructureSection>
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[[Category: Protease inhibitor]]
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[[Category: Human immunodeficiency virus 1]]
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[[Category: Large Structures]]
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[[Category: Chang SB]]
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[[Category: Das D]]
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[[Category: Garimella H]]
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[[Category: Ghosh AK]]
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[[Category: Kaufman JD]]
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[[Category: Mitsuya H]]
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[[Category: Wingfield PT]]
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[[Category: Yedidi RS]]

Current revision

Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir

PDB ID 4njt

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