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2efm

From Proteopedia

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(New page: 200px<br /><applet load="2efm" size="350" color="white" frame="true" align="right" spinBox="true" caption="2efm, resolution 1.50&Aring;" /> '''crystal structure an...)
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[[Image:2efm.jpg|left|200px]]<br /><applet load="2efm" size="350" color="white" frame="true" align="right" spinBox="true"
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#REDIRECT [[3lxs]] This PDB entry is obsolete and replaced by 3lxs
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caption="2efm, resolution 1.50&Aring;" />
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'''crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (WR483)'''<br />
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==About this Structure==
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2EFM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi] with <scene name='pdbligand=4MC:'>4MC</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Cruzipain Cruzipain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.51 3.4.22.51] Known structural/functional Sites: <scene name='pdbsite=AC1:4mc+Binding+Site+For+Residue+A+1300'>AC1</scene>, <scene name='pdbsite=AC2:4mc+Binding+Site+For+Residue+C+2300'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+1001'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+A+1002'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+C+1003'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+A+1004'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+A+1005'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+C+1006'>AC8</scene>, <scene name='pdbsite=AC9:So4+Binding+Site+For+Residue+A+1007'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+C+1008'>BC1</scene> and <scene name='pdbsite=BC2:Edo+Binding+Site+For+Residue+A+2960'>BC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFM OCA].
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[[Category: Cruzipain]]
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[[Category: Single protein]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Brinen, L.]]
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[[Category: Rickert, M.]]
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[[Category: 4MC]]
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[[Category: EDO]]
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[[Category: SO4]]
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[[Category: covalent inhibitor]]
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[[Category: cysteine protease]]
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[[Category: hydrolase]]
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[[Category: vinyl sulfonamide derived]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:58:03 2008''
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Current revision

  1. REDIRECT 3lxs This PDB entry is obsolete and replaced by 3lxs

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